2022 Acura MDX vs. 2021 Lexus RX

2022 Acura MDX vs. 2021 Lexus RX
2022 Acura MDX Standard


2021 Lexus RX 350

Starting MSRP

95 cubic feet

Maximum Cargo Capacity

56.3 cubic feet

Safety Technology

Lexus Safety System +
19 city mpg/26 hwy mpg**

Fuel Economy

20 city mpg/27 hwy mpg
3.5L V6 engine

Standard Engine

3.5L V6 engine
10-speed automatic transmission with Sequential SportShift Paddle Shifters


8-speed automatic electronically controlled transmission

Clovis drivers looking to add more luxury to their daily commute with a new SUV might be considering the Acura MDX vs. Lexus RX. If you just look at starting price, you’ll find the $46,900 MSRP* of the 2022 MDX Standard Package is slightly more than the starting price of $45,220 MSRP for the 2021 Lexus RX 350. However, the MDX features more substantial performance and cabin upgrades. Take a closer look at the Acura MDX vs. Lexus RX comparison from the automotive experts at Fresno Acura. 

Acura MDX vs. Lexus RX: Fuel Economy and Performance

No matter which crossover SUV you choose, you’ll have a similar fuel economy rating and identical base engines with V6 power for your Visalia commute. Despite some similarities, the MDX moves in its own lane with a more dependable automatic transmission over what’s available on the RX. You’ll even have the ability to upgrade your drivetrain on the MDX with the brand’s own Super-Handling All-Wheel Drive system. See the base specs of the Acura MDX vs. Lexus RX below:

2022 Acura MDX FWD Standard Package

  • 3.5L V6 engine
  • 10-speed automatic transmission 
  • 19 city mpg/26 hwy mpg rating**

2021 Lexus RX 350

  • 3.5L V6 engine
  • 8-speed automatic electronically controlled transmission 
  • 20 city mpg/27 hwy mpg rating

Acura MDX vs. Lexus RX: Standard Features and Cabin Space

When it comes to interior features of the MDX and Lexus RX, there are some you’ll find in each such as comfortable leather upholstery, Adaptive Cruise Control, satellite radio, and expanded passenger space. The MDX once again takes the lead by offering more storage room with its 95 cubic feet cargo capacity compared to the 56.3 cubic feet of cargo space featured in the Lexus RX. There are also several amenities offered in the MDX you won’t find in the Lexus RX which include:

  • Heated front seats
  • Automatic tilt away steering column
  • Power moonroof
  • 2nd-row 60/40 split-folding bench seat

Find the New Acura MDX for Sale at Fresno Acura

Now that you’ve had the chance to preview the new Acura MDX vs. Lexus RX 350, experience the difference on Madera roads with your very own Acura SUV. Bring home a new Acura MDX for sale from Fresno Acura and be sure to take a look at our new vehicle specials and national incentives to save on your next purchase. Speak with a member of our finance team who can answer your questions or you can apply for financing online at home. Contact us today for more information and to schedule a test drive at our dealership here in Fresno! Explore more ways this luxury SUV stands out with our breakdown of Acura MDX vs. Audi Q7.


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*Prices shown are Acura suggested retail prices only and do not include taxes, license or destination and handling charge. Destination & Handling charge for sedans (excluding PMC Edition) and SUVs (excluding PMC Edition) is $1,045.00. Destination & Handling charge for PMC Edition models and NSX is $1,995.00. Acura vehicle accessory costs, labor and installation vary. Dealers set their own prices. Please consult your selected dealer.

**Based on 2022 EPA mileage ratings. Use for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, battery pack age/condition (hybrid only) and other factors.

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